Articles tagged ”Application”

New reference of FabRICATOR in antibody based PET imaging

February 23, 2016 | References |

To develop an antibody based PET imaging for detection of amyloid beta in mouse models, Sehlin and colleagues  at the Rudbeck Laboratory in Uppsala, Sweden, used Fabricator to generate F(ab’)2 fragments. In the study, published in Nature Communications, Sehlin et al. generated F(ab’)2 fragments using FabRICATOR of an amyloid beta specific antibody and conjugated this to a transferrin receptor antibody for delivery across the blood brain barrier. Read more »